Therapeutic efficacy of neuregulin 1-expressing human adipose-derived mesenchymal stem cells for ischemic stroke.
Adipose-derived mesenchymal stem cells (AdMSCs) have been reported to ameliorate neurological deficits after acute ischemic stroke.As neuregulin 1 (NRG1, or heregulin 1), a growth factor cubs foam finger with versatile functions in the central nervous system, has demonstrated protective effects against ischemic brain injuries, we have generated NRG